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Angiogenesis : Cellular Therapy and Stem Cells for Graves disease stimulate the formation of new blood vessels (angiogenesis) in the thyroid gland, improving tissue perfusion and oxygenation

Lee PJ, Jiang BH, Chin BY, Iyer NV, Alam J, Semenza GL, Choi AM: Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia

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Safety depends on: Personal medical history Thyroid cancer history Pancreatitis history GI sensitivity Cardiovascular risk profile Both carry boxed warnings regarding thyroid C-cell tumors observed in animal studies