Rouphael C, DAmico G, Ricci K, Cywinski J, Miranda C, Koval C, Duggal A, Quintini C, Menon KVN, Miller C, Modaresi Esfeh J (2021) Successful orthotopic liver transplantation in a patient with a positive SARS-CoV2 test and acute liver failure secondary to acetaminophen overdose
Such linkers perform well in ADCs targeting endosomes or lysosomes, enabling rapid payload release after entering the cell
The compound is a small peptide fragment (di- or tripeptide) that uses transporter-mediated uptake
Melanocortin Peptide Research Guide An overview of PT-141 bremelanotide covering the melanocortin-4 pathway, its narrow approved medical use, and its research-use-only status in the UK