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These factors should be taken into consideration in future studies

The liver, as mentioned previously, is very important as it helps eliminate toxins from the body

We recently reported that NNMTi treatment combined with a low-fat, or lean, diet (LD) returned systemic adiposity and liver pathologies of obese animals to the adiposity and liver pathology levels of LD controls

Translational Relevance While preclinical studies are essential for understanding the mechanisms of action and potential therapeutic effects of Ipamrelin, the translation of these findings to human patients requires further clinical research