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Heartburn can occur after eating too much acidic, spicy, or high fat foods at one time like having spaghetti with tomato sauce for dinner, a glass of wine, salad with vinaigrette dressing, and a piece of rich chocolate cake for dessert

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Of the two conducted in Italy, the first concludes that clinical significance is yet to be evaluated and the second had no control group and the participants knew they were taking saffron