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11,12 Viral infections, such as hepatitis B and C, have previously been associated with decreased antioxidant capacity, as indicated by lower serum levels of glutathione, vitamin C, and vitamin E compared to those of healthy individuals

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Alcohol has been also found to enhanced production of hydrogen peroxide and OH like species (Dicker and Cederbaum, Oxidative stress dependent TRP channels and pain It is well known that ROS and RNS are produced in several physiological functions, such as mitochondrial and cytochromes P450 activities

10.3892/ol.2022.13224 128 ZhangR.PanT.XiangY.ZhangM.XieH.LiangZ.et al (2022b)