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When rabbit hippocampal cells are examined after a nictitating membrane conditioned response, up to three-fold activation of pkc is noted in synaptosomes of hippocampal CA1-3 regions (Sunayashiki-Kusuzaki et al., 1993), or to the stratum oriens of CA3 (Scharenberg et al., 1991), suggesting that pkc activity underlies associative learning processes