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The occurrence of ferroptosis in mature erythrocytes has not been confirmed and it seems quite challenging, since ferroptosis studies suffer from the lack of well-established markers and evaluation of this cell death requires a complex approach with identification of typical cellular and subcellular morphological alterations, genetic hallmarks, biochemical changes, expression of certain ferroptosis-related proteins, etc

On the contrary, cells treated with BSO maintained their nuclear glutathione level as well as the high expression of Id2 and normal cell growth

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Vitamin B12 deficiency in pregnancy can predispose women to pregnancy complications (such as preeclampsia or neural tube defects)