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Interest in such applications is largely driven by their proposed mechanisms of action, including enhancement of tissue repair, modulation of inflammation, and cytoprotective effects observed in preclinical studies

synthesized by certain bacteria Although the intestinal flora of humans is able to synthesize vitamin B 12 , humans are not able to absorb bacteria-generated vitamin B 12 since the location of synthesis (the colon) is too distal from the location of absorption (the small intestine)