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The ALDH18A1 gene is located on chromosome 10q24.1 and is composed of 17 exons that generate ten alternatively spliced mRNAs that collectively encode six distinct protein isoforms

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NAFLD is a common metabolic disorder associated with obesity and has a wide range of pathological alterations, such as fatty liver and nonalcoholic steatohepatitis (NASH), which contribute to hepatocellular carcinomas (HCCs)

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