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In conclusion, clinical trials for SCA3 have been sparse and underwhelming in terms of their power to detect change, yet there are several advances and opportunities that should allow for a sorely needed increase in the number of interventional studies that can be performed
These compounds come from different biological origins and modulate different molecular pathways, which is why researchers often use them in combination rather than as substitutes: BPC-157's distinguishing research angle is its gastric origin and mucosal-protection phenotype : it is the only compound in this cluster with published preclinical evidence in GI mucosa models, and the only one routinely studied under oral administration
10.1016/j.cmet.2015.05.023 19 CarruthersB
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