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3.1.2 Impaired adipogenesis in response to anti-inflammatory signals Contrary to the notion that inflammation plays a negative role in metabolism, some studies suggest that proinflammatory signals in the adipocytes are actually needed for functional adipose tissue homeostasis ( Figure 2 )

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Additional laboratory investigations examine cellular methylation-related pathways and NAD-associated signaling systems , which play a role in cellular energy dynamics and metabolic pathway coordination in controlled experimental settings