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When bile flow is impaired, toxins may accumulate in the liver or be reabsorbed in the intestines through enterohepatic recirculation , increasing systemic toxic burden (7)

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Biomarker testing may also take place periodically throughout your treatment so that your doctor can assess your response to the medicine.30 Dosing and administration A tesamorelin dose is usually 1-2mg by subcutaneous injection, the dosing frequency is either five or seven days a week, and each days dose is normally administered in the evening to coincide with the bodys natural growth hormone release pattern.28 Each dose is self-administered