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10.1186/s12871-020-00978-z 29

Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form

The considerable effects of non-selective TKIs, especially crizotinib, led to the US Food and Drug Administration (FDA) approval of crizotinib in ALK+ cancers [166]

Research involving this compound typically focuses on BPC-157 and TB-500 pathway-combination research, with attention to receptor activity, cellular signaling, and measurable pathway response in experimental models