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Notably, HGF is implicated in guiding spinal motoneurons to their target muscles in the limbs (Ebens et al., 1996)

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3.2 Tumor angiogenesis The zebrafish xenotransplantation model capitalizes on its physiologically simplified circulatory system, optical transparency during embryogenesis, and transgenic fluorescent vascular reporters to enable real-time visualization of tumor-associated angiogenesis

Finally, NPs have been associated with multiple cell death pathways, including ferroptosis (via p53-mediated ferritinophagy and GPX4 depletion), pyroptosis (via TSC2/TFEB-related lysosomal defects), and intrinsic apoptosis, indicating context-dependent terminal outcomes for neuronal homeostasis ( 3.5 Changes in neurotransmitter and synaptic function Understanding how MPs and NPs affect neurotransmission requires reconciling limited and often conflicting evidence, which currently points to a highly context-dependent nature of neurotoxicity