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Description

Functional Expression of Carnitine/organic Cation Transporter OCTN1/SLC22A4 in Mouse Small Intestine and Liver

2016;12:e1006391

These results directly confirm that excessive NNMT activation suppresses NAD+ synthesis and impairs energy metabolism, while NNMT inhibition effectively reverses this process, establishing NNMT as a negative regulator of energy metabolism