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It means the evidence base is still developing

Possible long-term risks of vitamin B12 Most side effects of high doses of B12 are rare and temporary

Certain individuals are more likely to develop B12 deficiency, including those with: Pernicious anemia Gastrointestinal conditions (such as Crohns disease or celiac disease) A history of gastrointestinal surgery Difficulty absorbing nutrients due to age or other medical conditions For these patients, vitamin B12 injections are an effective option because they deliver the nutrient directly into the bloodstream, bypassing the digestive system and ensuring optimal absorption

Each injection remains 3.2 mg while frequency falls