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With tirzepatides recent approval to treat OSA in patients with obesity, sleep medicine providers must educate themselves and their patients on the risks and benefits of medications from compounding pharmacies

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Oral supplementation (50150 g daily) may suit dietary deficiency without nerve involvement, but malabsorption cases require injections

Further cysteine-rich protein motifs that can be modified by electrophiles such as EdAG are the Zn-binding Cys 2 His 2 and Zn 2 /Cys 6 domains ( zinc finger ) of regulatory proteins such as nuclease enzymes, of DNA transcription factors and of metallothioineins [146,147]