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For example, using single-cell RNA sequencing technology, a precise cell map of TME of patients can be drawn, revealing the interacting cell subpopulations and their specific surface markers in the tumor [264]

Finally, examples of pH-sensitive linkers are usually found in hydrazone-based linkers that can hydrolyze in the more acidic environment of the lysosome

While TGF-1 induced slightly higher levels of phosphorylation than Gepon, both agents clearly engaged this non-canonical signaling axis

In man serum fasting levels of inorganic sulfate were shown to increase with age and exhibit a circadian rhythm, probably associated with food intake