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Some physicians would start colchicine after one very severe or two moderately severe attacks of gout, and beyond that, use allopurinol

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10.1038/s41419-023-06106-2 38 ChuM.AnX.FuC.YuH.ZhangD.LiQ.et al (2023)

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MCT1 also requires an ancillary protein, CD147, for correct trafficking to the plasma membrane as well as functional activity (Wilson et al

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