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Raises NAD+ and SAM The same study showed that NAD+ and S-adenosyl-methionine (SAM) both went up after NNMT inhibition

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Administration Route by Peptide Type When Injectable GHK-CU Makes Sense The injectable form provides systemic benefits that topical cannot achieve: Whole-body tissue regeneration effects Internal organ support Consistent blood levels Better bioavailability Combined with other injectable peptides When Topical Makes Sense Topical application excels for: Targeted skin treatment Hair and scalp applications Those avoiding injections Combination with skincare routines Localized wound healing For maximum benefit, some protocols use both injectable GHK-CU for systemic effects and topical copper peptides for targeted skin benefits