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Whether oral BPC-157 produces significant systemic effects beyond the GI tract through mucosal absorption remains an area of active research: some preclinical studies suggest systemic effects at higher doses, but the primary clinical rationale for oral administration is local gut action

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Cai, C., Meng, C., He, S., Gu, C., Lhamo, T., Draga, D., Luo, D., Qiu, Q., Cai, C., Meng, C., He, S., Gu, C., Lhamo, T., Draga, D., Luo, D., & Qiu, Q