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Oral formulations are designed to survive the stomach acid and are better suited for addressing systemic inflammation and gastrointestinal issues like ulcers or inflammatory bowel disease

For procedures requiring gastric emptying or precise timing of oral medication administration, such as upper endoscopy or surgery requiring general anesthesia, the delayed gastric emptying effect of semaglutide may need to be considered

Standard good laboratory practice (GLP) diet and fresh water were provided ad libitum

For individuals who want to maintain normal eating patterns, avoid central appetite manipulation, cannot tolerate GLP-1 side effects, or prefer targeted fat metabolism enhancement without hunger modification, AOD-9604 offers an alternative mechanism