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bioRxiv2024 May 1

TFAM binds mtDNA with high affinity and promotes both replication and transcription of the mitochondrial genome, thereby supporting the synthesis of electron transport chain complexes, ribosomal RNAs, and tRNAs required for the generation of new, functional mitochondria ( Importantly, this cascade is self-limited and context-dependent

By boosting glutathione production, insulin sensitivity can be improved, helping the body manage blood sugar levels more effectively and function as it should

[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Jelovac N., Sikiric P., Rucman R., Petek M., Perovic D., Konjevoda P., Marovic A., Seiwerth S., Grabarevic Z., Sumajstorcic J., et al