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The metal chelating activity of flavonoids results either (i) in the formation of metal-chelates which have lower catalytic efficiency in Fenton reaction than pure flavonoids (decreased number of metal binding sites is usually associated with lower catalytic activity) or (ii) metal flavonoid chelates can intercalate into DNA of cancer cells, triggering cell death (Simunkova et al

The other hallmark feature of ADthe amyloid plaqueforms from -amyloid (A), a small peptide derived from cleavage of amyloid precursor protein (APP)

Open communication with healthcare providers, realistic weight loss expectations (0.5-1kg weekly as per NHS guidance), and attention to overall wellbeing rather than rapid results will optimise both metabolic and reproductive outcomes during weight loss injection therapy

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