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Interestingly, the existence of harmful concentrations of diethylene glycol, a known cytotoxic agent, in e-liquid aerosols is contentious with some studies detecting its presence [4, 68, 70,71,72], and others finding low subtoxic concentrations [73, 74]

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Some studies have shown that dual use of e-cigarettes and combustible cigarettes actually increases risk for some of the diseases associated with cigarette smoking