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Sleep disorders and sleep effect in Parkinson's disease

A randomized controlled trial of oral crocin from saffron (30 mg/day) versus placebo for eight weeks in 177 cancer patients who had been experiencing symptoms of CIPN for at least a month reported that patients who received saffron tablets had lower levels of sensory, motor, and neuropathic pain, with similar side effects to placebo (Bozorgi 2021)

Vitamin B12 injections are commonly used to support energy levels, red blood cell production, and nervous system health

Decreased insulin-mediated suppression of adipocyte lipolysis has been reported in obese rats (118) as well as in women with visceral obesity (3, 54), although several other studies in humans report that the antilipolytic effects of insulin are well conserved, even in subjects with highly impaired insulin-mediated glucose regulation (7, 8, 11, 52)