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These dynamic metabolic variations directly influence drug distribution, target expression, and therapeutic response, posing significant challenges to the development of effective personalized treatment strategies [15, 18, 21]

Also, in Hevea brasiliensis, various stress treatments or mediators (drought, wounding, H 2 O 2 , methyl jasmonate) induce the mRNA level of a chloroplastic GR isoform [134]

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A cerato-platanin protein SsCP1 targets plant PR1 and contributes to virulence of Sclerotinia sclerotiorum