Recent advances in virology and mucosal immunology make this question biologically plausible and experimentally tractable
Smoking rates have decreased in the United States in recent years, yet the mortality rate associated with tobacco addiction is still staggering, with more than 480,000 premature deaths in the United States each yearabout 1 in every 5 deaths.5 Tobacco use killed approximately 100 million people during the 20th century and, if current smoking trends continue, the cumulative death toll for this century is projected to reach 1 billion.8 More information can be found at www.drugabuse.gov/drugs-abuse/tobacco-addiction-nicotine
Low-Back Pain : Common in cyclists due to prolonged bending and lower back stress, this pain can be exacerbated by poor posture, a non-ergonomic bike setup, or weak core muscles
The Law Firm of Pun, Pun, and Wordplay: When Jack defends his ward Cecily's social status against Lady Bracknell's questions, he notes the late Thomas Cardew's three addresses (which "always inspire confidence, even among tradesmen," according to Lady Bracknell)