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136 In addition, acquired astrocytopathies are prominent in hepatic encephalopathy (in which astrocytes lose their homoeostatic capabilities 137 ) and in neuromyelitis optica, in which the astrocyte protein, AQP4 is the subject of autoimmune attack, leading to dysfunction and death of astrocytes resulting in pronounced inflammation and degeneration of neural tissue

Curcumin can directly neutralize ROS and reactive nitrogen species, reducing oxidative damage to lipids, proteins, and DNA in dopaminergic cells (70)

The concept of tendon rupture is described as a complete disruption of the continuity of the tendon fibers connecting the muscle to the bone

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