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Both alcohol and tobacco smoke induce certain cytochrome P450 enzymesparticularly CYP2E1 (by ethanol) and CYP1A2 (by tobacco smoke)which can lead to altered drug metabolism and increased production of toxic intermediates

The process uses solvents that can reach into the fibers more effectively than water-based methods, ensuring the smell is thoroughly eliminated

Among women, prevalence of smoking is highest in Europe and Central Asia (21 percent), followed by North America (18 percent), while less than 3 percent of women smoke in South Asia, Sub-Saharan Africa, Middle East and North Africa, and East Asia and Pacific.

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