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For acclimatization, C57BL6/N adult male mice (Charles River, Lyon, France) were housed for at least 1 week in standard housing conditions in the Animal Research Institute AMC (ARIA) before experiment
In controlled laboratory conditions, it may be included in experimental studies examining peptide stability, structural characteristics, and molecular interaction behavior
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Normally, the excess of ROS in the mitochondria is neutralized by the endogenous antioxidant system which comprises several enzymes and non-enzymatic antioxidants [100] including reduced glutathione (GSH), vitamins C, and E, the Cu/Zn-superoxide dismutase (SOD) in the cytoplasm, and Mn-SOD in the mitochondrial matrix, catalase in the peroxisomes, glutathione peroxidase (GSH-Px), etc
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