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Aging and atherosclerosis: vascular intrinsic and extrinsic factors and potential role of IL-6

Issa GC, Cuglievan B, DiNardo CD, MD, MSc, Short NJ, MD, McCall D, MD, Gibson A, DO, Nunez C, MD, Garcia MB, DO, Roth M, MD, Bidikian A, MD, Pike A, RN, Tan S, RN, Kammerer B, BSN, MS, RN, Yilmaz M, MD, Kadia TM, MD, Pemmaraju N, MD, Ohanian M, DO, Daver N, MD, Jabbour E, Borthakur G, MD, Ravandi F, MD, MBBS, Garcia-Manero G, MD, Andreeff M , PhD MD, Kantarjian HM, MD

Over time, this routine not only reduces melanin pigmentation but also improves skin texture, firmness, and overall health

Inflammatory and Cytokine Signaling Genes: In cell culture models of inflammation (e.g., LPS-stimulated macrophages or keratinocytes), GHK-Cu has been investigated for its capacity to suppress the expression of pro-inflammatory cytokines like IL-6 and TNF-