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The body synthesizes glutathione through the -glutamyl cycle , which involves three key enzymatic reactions: 1

The polymorphic human glutathione transferase T1-1, the most efficient glutathione transferase in the denitrosation and inactivation of the anticancer drug 1,3-bis(2-chloroethyl)-1-nitrosourea

According to a study by Hendrickson titled What is the most appropriate dose of N-acetylcysteine after massive acetaminophen overdose? published in Clinical Toxicology (2019), medical interventions such as N-acetylcysteine (NAC) treatment have been effective in reversing acetaminophen toxicity when administered promptly

That is, in the TEM image, the discrepancy is caused by electron dispersal