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28 However, oral therapy does not improve serum methylmalonic acid levels as well as intramuscular therapy, although the clinical relevance is unclear

The outcomes are consistent with melittin activating calcium channels, increasing Ca 2+ concentrations inside the cells, and calcium-responsive CaMKII (Balasubramani et al., 2023)

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This rhythm is thought to maintain your bodys responsiveness to the peptide over time