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The RBC has little biosynthetic activity, but still shunts about 10% of glucose through the pentose phosphate pathway, in this case almost exclusively for the production of NADPH

The formation of self-propagating aggregates by the yeast prion proteins generally leads to a loss-of-function of the native protein and subsequently the appearance of a novel phenotype, which can be transmitted to daughter cells and meiotic progeny by cytoplasmic inheritance (Liebman and Chernoff, 2012

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