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Some people report mostly stimulating effects when they smoke, like feeling more aware, creative, motivated, or talkative, and others describe the opposite, reporting it makes them lazy, drowsy, hungry, and couch-locked. 5 The Depressant Effects of Weed Weed can have depressant effects, causing people to feel sluggish, slow, drained, and unmotivated

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It can also lead to kidney disease, liver disease, and side effects like nausea and headaches