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Conservative estimate: 28 days refrigerated at 2-8 degrees Celsius (36-46 degrees Fahrenheit) Extended estimate: Up to 60 days under ideal storage conditions At low doses, the math does not work

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In the few individuals who did have preexisting cross-reactive antibodies, these often targeted the S2 region of spike that is more conserved across coronaviruses but that predominantly induces nonneutralizing antibodies [72, 73]