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The preservative load suppresses these inputs but eventually depletes against repeated insults

Membrane-active metallopolymers: repurposing and rehabilitating antibiotics to gram-negative superbugs

The molecular mechanisms proposed to explain how ROS could specifically mediate brain damage are the following: (1) The lower levels of antioxidants can promote increased activity of lipoxygenase in CNS stimulating leukotriene production, thereby increasing the immunoinflammatory processes in the cerebral cortex

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