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In one study there was no detectable change in retinal blood flow until the mean brachial artery blood pressure was elevated to an average of 115 mm Hg, which represented an average rise in mean blood pressure of 41% above baseline values 28

And a much better profit than cigarettes ever brought, given the lack of taxes levied upon them (for now)

APEJ Next-Generation Cigarettes Market Statistics APAC next-generation cigarette market is anticipated to record significant growth during the forecast period, influenced by rapid urbanization, growing disposable income, and growing health awareness