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The control + DSS mice contained much lower abundance of known mouse commensal taxa and higher abundance of the Clostridium sensu stricto clade (54), which contains known pathogens such as Clostridium perfringens (55), and well-known butyrate-producing symbionts, such as Clostridium butyricum (46)

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A.2001Cholesterol and hydroxycholesterol sulfotransferases: identification, distinction from dehydroepiandrosterone sulfotransferase, and differential tissue expression.1427(July 2001),29782984,0013-7227 55

These observations are consistent with emerging evidence connecting systemic metabolism, microbiome-derived metabolites, and neurological function 65,66 , and suggest that metabolic flexibility may contribute to recovery potential