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[Confidence: Medium] Organ-Specific Targeting: By isolating the hippocampus, the researchers confirmed that GHK-Cu can cross the blood-brain barrier (or bypass it via olfactory tracts) to modulate neuroinflammation and synaptic plasticity, which are critical bottlenecks in age-related cognitive decline

Potential Implications: The peptides efficacy in healing gastrointestinal fistulas and anastomoses suggests potential therapeutic applications in related conditions

295 , E92E102 (2008)

Bertolo A, Mehr M, Aebli N, Baur M, Ferguson SJ, Stoyanov JV: Influence of different commercial scaffolds on the in vitro differentiation of human mesenchymal stem cells to nucleus pulposus-like cells