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456 Additionally, metabolic diseases are often correlated with a series of complications, increasing mortality, and medical costs

In conclusion, we found for the first time that LC and TAU have synergistic inhibitory effects on the proliferation and calcification of VSMCs and that the up-regulation of TAUT expression and TAU uptake by LC in VSMCs may be involved in the synergistic action

Depletion applies to non-renewable assets (like natural resources)

Perturbed sphingolipid and phospholipid metabolism led to the upregulation of apoptogenic ceramides and the downregulation of lipids involved in vital cerebral functions, such as neurotransmission, anti-inflammation, and synaptic refinement