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Such a limitation is unavoidable: comparisons between different methods to estimate smoking-attributable mortality did not reveal a best-practice method [46, 47], and even if good estimates of smoking prevalence are available to potentially directly estimate smoking-attributable mortality, other factors like smoking intensity are often harder to measure and to take into account in direct estimates

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E-liquid comes in a variety of flavors, which can provide a different experience than what is typically associated with cigarettes