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This results from a tyramine-induced depletion of norepinephrine normally present in the readily releasable vesicle pool, and replacement of vesicular norepinephrine with tyramine (which functions as a false- or pseudo- neurotransmitter), which when released has no effect on postsynaptic adrenergic receptors (Figure 1)

Future research should also prioritize the identification and optimization of natural compounds with favorable pharmacokinetic profiles, low toxicity, and minimal risk to reproductive function

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The role that resveratrol exerts on aging is not fully understanding yet