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While cigarettes still comprise almost 90% of all tobacco sales in the US, other tobacco products also weigh heavily on the environment 13 billion cigars and over 128 million pounds of smokeless tobacco were sold in the US last year

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In the aforementioned study exposing human gingival fibroblasts to CS condensate or to nicotine-rich or nicotine-free e-vapour condensates [29], the detrimental effects were greater in cells exposed to nicotine-rich condensate than to nicotine-free condensate, suggesting that the possible injurious effects of nicotine should be considered when purchasing e-refills