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Microbiota-targeted therapeutic strategies and clinical trials Building upon mechanistic understanding, this section synthesizes interventional strategies targeting the MGBA

The SURMOUNT program (obesity) added thousands more, including the head-to-head SURMOUNT-5 trial against semaglutide

441 Lithium also regulates astrocytic morphology through the extracellular matrix regulatory enzyme lysyl oxidase (LOX) and peroxisome proliferator-activated receptor , with LOX being the most highly regulated lithium-responsive astroglial gene