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The treatment will leave the skin mildly red and may result in pinpoint bleeding or blistering

The most common vitamin B12 deficiency symptoms are: Fatigue Weakness Loss of appetite Weight loss Numbness and tingling in the hands and feet Soreness of the mouth or tongue A pale yellow tinge to your skin Difficulty maintaining balance Disturbed vision Depression Confusion Poor short-term memory A severe vitamin B12 deficiency can cause megaloblastic anemia, also known as vitamin B12 deficiency anemia, where red blood cells are not produced properly and are larger than normal

Questions remaining include optimal human dosing, long-term safety, effects across different populations, interactions with diet and exercise, and whether benefits extend beyond weight loss to improvements in cardiometabolic disease outcomes