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Cell Tissue Res 311:19 [DOI] [PubMed] [Google Scholar] Wayman GA, Davare M, Ando H, Fortin D, Varlamova O, Cheng H-YM, Marks D, Obrietan K, Soderling TR, Goodman RH, et al

(PubMed) MacEvilly CJ, Muller DP

At doses that are above the safe maximum level (overdose), opioids can cause extremely slow breathing, reducing the amount of oxygen getting to the brain below the amount needed to stay alive and causing death

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