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Methotrexate (MTX) is a cornerstone drug in the treatment of RA, primarily functioning through multiple mechanisms: inhibiting the production of pro-inflammatory cytokines, modulating the Th1/Th2 balance, and suppressing the proliferation of immune cells like T and B cells

Here's the mechanism: the enzyme ALDH2 (aldehyde dehydrogenase 2) oxidises acetaldehyde into acetic acid, but this process requires adequate glutathione reserves to neutralise reactive oxygen species (ROS) generated during the reaction

*Please note that this product is intended for adults only

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