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Glutathione supplement serves as an ant-oxidant in the liver

J Nutr Health Aging 20(8):825834

3.6 Ferroptosis: iron-dependent cell death Ferroptosis, a non-apoptotic form of regulated cell death involving iron ions and lipid peroxidation, is characterized primarily by the accumulation of lipid peroxides in the cell membrane ( Recent studies have indicated that ferroptosis, as an important mechanism of melanocyte destruction, not only directly leads to cell death but also intensifies the inflammatory response and immune dysregulation in vitiligo by enhancing oxidative stress and activating innate immune pathways ( + T cell response against melanocytes

These models replicate pathological conditions such as POI, polycystic ovary syndrome, and iatrogenic ovarian failure through diverse approaches, including chemical, nutritional, surgical, genetic, and toxicological methods